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Semaglutide

Semaglutide

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Semaglutide is a GLP-1 receptor agonist that has emerged as a cornerstone in the scientific exploration of metabolic function and appetite regulation. This synthetic analog of the human incretin hormone GLP-1 is specifically engineered for enhanced stability, allowing for extended duration of action during laboratory protocols.

Product Summary

Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist developed for the study of metabolic regulation, glucose homeostasis, and appetite control. This research compound mimics endogenous incretin hormones to promote insulin secretion and suppress glucagon release in a glucose-dependent manner. Extensively studied for its effects on weight modulation and type 2 diabetes pathways, Semaglutide represents a cutting-edge tool for investigators exploring obesity, insulin sensitivity, and endocrine signaling.

– Form: Lyophilized peptide
– Purity: ≥99%
– Origin: Manufactured and tested in the USA
– Certifications: Certificate of Analysis (COA) included with every order

Semaglutide selectively binds to and activates the GLP-1 receptor, a G protein-coupled receptor expressed in the pancreas and central nervous system. Upon activation:
– Enhances insulin secretion from pancreatic β-cells in a glucose-dependent manner
– Suppresses glucagon release during hyperglycemia
– Slows gastric emptying, leading to prolonged satiety
– Reduces appetite via central hypothalamic pathways

– Metabolic disease modeling
– Appetite and weight regulation studies
– Insulin-glucose homeostasis research
– Pancreatic β-cell activity
– Neuroendocrine signaling pathways

– Stable GLP-1 analog with extended half-life
– Consistent bioavailability in vivo and in vitro
– Well-documented clinical analog for translational studies
– High reproducibility across experimental setups

Each vial is:
– Manufactured in a GMP-compliant U.S. facility
– Accompanied by a Certificate of Analysis (COA)
– Subjected to HPLC and mass spectrometry verification
– Shipped from within the United States for quality control

– Contents: 5mg of lyophilized Semaglutide peptide
– Appearance: White/off-white powder
– Solubility: Sterile bacteriostatic water or acetic acid recommended
– Storage: Store lyophilized vial at -20°C; reconstituted solution stable up to 30 days when refrigerated
*For laboratory research use only. Not intended for human or veterinary use.*

– This product is sold for research purposes only
– Not for human consumption, injection, or diagnostic procedures
– Must be handled by qualified professionals in accordance with institutional and governmental safety guidelines

🧬 Semaglutide — Frequently Asked Questions (FAQ)

Semaglutide is a GLP-1 receptor agonist commonly researched for its effects on glucose metabolism, insulin secretion, and appetite regulation. It is a synthetic analog of human GLP-1 with extended half-life for weekly dosing.

Semaglutide binds to GLP-1 receptors in the pancreas, brain, and GI tract. This stimulates insulin secretion, suppresses glucagon release, delays gastric emptying, and reduces appetite. These effects contribute to improved glycemic control and potential weight loss in preclinical models.

Our Semaglutide is offered as a lyophilized powder in sterile, sealed vials for laboratory research purposes only. Each batch is produced and tested in the USA.

No. Semaglutide sold by Legion Peptides is strictly intended for laboratory research. It is not approved for human or veterinary use.

Lyophilized Semaglutide should be stored at -20°C in a dry environment. Once reconstituted, store at 2–8°C and use promptly, following your lab’s guidelines for stability.

Every vial is >98% pure, verified by HPLC and Mass Spectrometry. A certificate of analysis (COA) is included with each purchase.

Semaglutide is shipped in temperature-resistant packaging to maintain integrity. Cold-chain shipping is available for bulk or high-sensitivity orders upon request.

Semaglutide is often studied alongside compounds like Cagrilintide and Tirzepatide for synergistic metabolic effects. Always follow approved research protocols when combining peptides.

Visit our Lab Test Results page, select Semaglutide from the dropdown, and submit your name and email to receive the COA directly.

Our Semaglutide is U.S.-made, lab-verified, and backed by superior customer service. Fast shipping, premium purity, and research-only quality make us the preferred choice.

🧬 Semaglutide — Frequently Asked Questions (FAQ)

Semaglutide is a GLP-1 receptor agonist commonly researched for its effects on glucose metabolism, insulin secretion, and appetite regulation. It is a synthetic analog of human GLP-1 with extended half-life for weekly dosing.
Semaglutide binds to GLP-1 receptors in the pancreas, brain, and GI tract. This stimulates insulin secretion, suppresses glucagon release, delays gastric emptying, and reduces appetite. These effects contribute to improved glycemic control and potential weight loss in preclinical models.
Our Semaglutide is offered as a lyophilized powder in sterile, sealed vials for laboratory research purposes only. Each batch is produced and tested in the USA.
No. Semaglutide sold by Legion Peptides is strictly intended for laboratory research. It is not approved for human or veterinary use.
Lyophilized Semaglutide should be stored at -20°C in a dry environment. Once reconstituted, store at 2–8°C and use promptly, following your lab’s guidelines for stability.
Every vial is >98% pure, verified by HPLC and Mass Spectrometry. A certificate of analysis (COA) is included with each purchase.
Semaglutide is shipped in temperature-resistant packaging to maintain integrity. Cold-chain shipping is available for bulk or high-sensitivity orders upon request.
Semaglutide is often studied alongside compounds like Cagrilintide and Tirzepatide for synergistic metabolic effects. Always follow approved research protocols when combining peptides.
Visit our Lab Test Results page, select Semaglutide from the dropdown, and submit your name and email to receive the COA directly.
Our Semaglutide is U.S.-made, lab-verified, and backed by superior customer service. Fast shipping, premium purity, and research-only quality make us the preferred choice.

Reviews

J.L. Researcher
J.L. ResearcherBoston
Shipping was fast and the product came safely packed. Mixed easily and looked great.
Anika P
Anika PSan Francisco
Been using this for weight-related studies—really clean and easy to work with.
Daniel K
Daniel KSeattle
Showed great consistency across multiple experiments. Perfect for appetite-focused research.
Fatima H
Fatima HChicago
Love how smooth it was to prepare. Definitely helped us continue our work on GLP-1 effects.
 Carlos M
Carlos MMiami
One of the best I've used for body weight management models in research.
Sarah T
Sarah TDenver
Super professional packaging and the quality held up well in our long-term tests.
Mohammed A
Mohammed AHouston
Easy to measure and use. Excellent option for weight loss-related pathways.
Emily N
Emily NPhiladelphia
Exactly what I needed to explore hunger and energy balance in our study.
Raj S
Raj SNew York
Held up nicely over time. We used it for tracking changes in food intake behavior.
Luis V
Luis VPhoenix
Great all-around. Helped us make progress on GLP-1 linked mechanisms.
Jin L
Jin LLos Angeles
Very stable and clean. Ideal for learning more about satiety-related responses.
Nina D
Nina DMinneapolis
Simple to work with and came with all the right paperwork.
Victor R
Victor RAtlanta
Reliable and good quality. Useful for studying energy metabolism.
Khadija B
Khadija BDetroit
A trusted pick for anyone exploring weight control research.
Andrew F
Andrew FAustin
Easy to prepare, and support was helpful when I had questions.

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