Semaglutide

Description

High-Level Summary

Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist developed for the study of metabolic regulation, glucose homeostasis, and appetite control. This research compound mimics endogenous incretin hormones to promote insulin secretion and suppress glucagon release in a glucose-dependent manner. Extensively studied for its effects on weight modulation and type 2 diabetes pathways, Semaglutide represents a cutting-edge tool for investigators exploring obesity, insulin sensitivity, and endocrine signaling.

– Form: Lyophilized peptide
– Purity: ≥99%
– Origin: Manufactured and tested in the USA
– Certifications: Certificate of Analysis (COA) included with every order

Mechanism of Action (MOA)

Semaglutide selectively binds to and activates the GLP-1 receptor, a G protein-coupled receptor expressed in the pancreas and central nervous system. Upon activation:
– Enhances insulin secretion from pancreatic β-cells in a glucose-dependent manner
– Suppresses glucagon release during hyperglycemia
– Slows gastric emptying, leading to prolonged satiety
– Reduces appetite via central hypothalamic pathways

Research Applications

– Metabolic disease modeling
– Appetite and weight regulation studies
– Insulin-glucose homeostasis research
– Pancreatic β-cell activity
– Neuroendocrine signaling pathways

Key Benefits for Research

– Stable GLP-1 analog with extended half-life
– Consistent bioavailability in vivo and in vitro
– Well-documented clinical analog for translational studies
– High reproducibility across experimental setups

Certificate of Purity & Testing

Each vial is:
– Manufactured in a GMP-compliant U.S. facility
– Accompanied by a Certificate of Analysis (COA)
– Subjected to HPLC and mass spectrometry verification
– Shipped from within the United States for quality control

Formulation & Dosage Info

– Contents: 5mg of lyophilized Semaglutide peptide
– Appearance: White/off-white powder
– Solubility: Sterile bacteriostatic water or acetic acid recommended
– Storage: Store lyophilized vial at -20°C; reconstituted solution stable up to 30 days when refrigerated
*For laboratory research use only. Not intended for human or veterinary use.*

Legal & Compliance Notices

– This product is sold for research purposes only
– Not for human consumption, injection, or diagnostic procedures
– Must be handled by qualified professionals in accordance with institutional and governmental safety guidelines