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PEG-MGF (Mechano Growth Factor)

PEG-MGF (Mechano Growth Factor)

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PEG-MGF is a pegylated IGF-1 variant designed for an extended half-life. It is studied primarily for muscle repair, regeneration, and growth by activating satellite cells and stimulating protein synthesis.

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Description

High-Level Summary

PEG-MGF (Pegylated Mechano Growth Factor) is a synthetic variant of IGF-1 (insulin-like growth factor) with a PEG (polyethylene glycol) modification to extend its half-life. It is studied primarily for its role in muscle repair, regeneration, and growth. PEG-MGF activates satellite cells in muscle tissue, stimulating protein synthesis and muscle fiber hypertrophy following mechanical stress or injury.

– Form: Lyophilized peptide
– Purity: >99%
– Origin: Manufactured and tested in the USA
– Certifications: Certificate of Analysis (COA) included

Mechanism of Action (MOA)

PEG-MGF promotes muscle regeneration by triggering satellite cell activation and proliferation. It mimics the natural MGF splice variant of IGF-1, which is expressed in response to mechanical overload. The PEGylation protects the peptide from rapid degradation, extending its half-life and making it more viable for research applications involving sustained activity.

Research Applications

– Muscle recovery and rehabilitation
– Resistance training and overload models
– Muscle wasting and sarcopenia studies
– Performance and regenerative optimization
– Tissue repair and cellular regeneration research

Key Benefits for Research

– Longer half-life due to PEGylation
– Stimulates muscle-specific stem cell activity
– Supports tissue regeneration post-exercise or injury
– Mimics naturally occurring IGF-1 splice variant

Certificate of Purity & Testing

Each vial is:
– Produced in a GMP-compliant U.S. facility
– Accompanied by a Certificate of Analysis (COA)
– Verified via mass spectrometry and HPLC
– Shipped with quality control documentation

Formulation & Dosage Info

– Contents: 1mg PEG-MGF lyophilized powder
– Appearance: White or off-white powder
– Solubility: Reconstitute with sterile bacteriostatic water
– Storage: Store at -20°C; refrigerate after reconstitution and use within 30 days
*For research use only. Not for human or veterinary use.*

Legal & Compliance Notices

– Sold for laboratory research purposes only
– Not intended to treat, diagnose, or prevent disease
– Buyer assumes responsibility for safe handling and use

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