Description
High-Level Summary
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-C) is a mitochondrial-derived peptide that plays a unique role in metabolic regulation, stress resistance, and cellular homeostasis. Expressed from mitochondrial DNA, MOTS-c is emerging as a key factor in studies of aging, energy regulation, and exercise physiology. It modulates nuclear gene expression, improves insulin sensitivity, and enhances cellular stress responses, making it a powerful tool for research into metabolic diseases, sarcopenia, and mitochondrial function.
– Form: Lyophilized peptide
– Purity: ≥99%
– Origin: Manufactured and tested in the USA
– Certifications: Certificate of Analysis (COA) included with every order
Mechanism of Action (MOA)
MOTS-c exerts its effects by:
– Activating AMPK signaling to regulate energy balance
– Enhancing glucose uptake and fatty acid oxidation
– Promoting mitochondrial biogenesis and function
– Modulating stress adaptation genes in the nucleus
– Supporting skeletal muscle resilience and insulin sensitivity
Research Applications
– Metabolic syndrome and obesity models
– Mitochondrial function and biogenesis research
– Exercise mimetic and endurance studies
– Insulin resistance and glucose metabolism studies
– Aging and cellular stress response models
Key Benefits for Research
– Mitochondrial origin peptide with systemic regulatory effects
– Strong preclinical support in energy metabolism and aging
– Enhances metabolic flexibility and exercise endurance
– Exceptional stability and purity for research integrity
Certificate of Purity & Testing
Each vial is:
– Manufactured in a GMP-compliant U.S. facility
– Accompanied by a Certificate of Analysis (COA)
– Subjected to HPLC and mass spectrometry verification
– Shipped from within the United States for quality control
Formulation & Dosage Info
– Contents: 5, 10, 20mg of lyophilized MOTS-c peptide
– Appearance: White/off-white powder
– Solubility: Sterile bacteriostatic water recommended
– Storage: Store lyophilized vial at -20°C; reconstituted solution stable up to 30 days when refrigerated
*For laboratory research use only. Not intended for human or veterinary use.*
Legal & Compliance Notices
– This product is sold for research purposes only
– Not for human consumption, injection, or diagnostic procedures
– Must be handled by qualified professionals in accordance with institutional and governmental safety guidelines
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