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LL-37

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LL-37 is a human antimicrobial peptide that provides innate immune defense. It’s studied for its ability to disrupt microbes, modulate immune response, and accelerate tissue repair.

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Description

High-Level Summary

LL-37 is a human cathelicidin antimicrobial peptide that plays a critical role in the body’s innate immune defense. It is studied for its ability to disrupt microbial membranes, modulate immune responses, and accelerate tissue repair and regeneration. LL-37 is a subject of interest in wound healing, dermatology, and infectious disease models.

– Form: Lyophilized peptide
– Purity: >99%
– Origin: Manufactured and lab-tested in the USA
– Documentation: Certificate of Analysis (COA) included

Mechanism of Action (MOA)

LL-37 exerts its antimicrobial activity by binding to and disrupting bacterial membranes. It also modulates host cell signaling by influencing cytokine production, angiogenesis, and epithelial repair. This dual function makes LL-37 a powerful peptide for immune defense and wound regeneration research.

Research Applications

– Bacterial, viral, and fungal infection models
– Chronic wound healing studies
– Inflammatory skin disorder research
– Biofilm disruption and microbiome modulation
– Innate immune system enhancement

Key Benefits for Research

– Broad-spectrum antimicrobial action
– Enhances epithelial cell migration and healing
– Modulates inflammation and cytokine response
– Promotes tissue regeneration and angiogenesis

Certificate of Purity & Testing

Each vial is:
– Produced in a GMP-compliant U.S. facility
– Accompanied by a Certificate of Analysis (COA)
– Verified via HPLC and mass spectrometry
– Shipped securely with quality-control documentation

Formulation & Dosage Info

– Contents: 10mg LL-37 lyophilized peptide
– Appearance: White to off-white crystalline powder
– Solubility: Reconstitute with sterile bacteriostatic water
– Storage: Store lyophilized at -20°C; refrigerate after reconstitution and use within 30 days
*For research use only. Not for human or veterinary consumption.*

Legal & Compliance Notices

– Intended for laboratory research only
– Not approved for human consumption or clinical use
– Buyer assumes all responsibility for research use and compliance

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