Description
High-Level Summary
IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1) is a modified version of human IGF-1 designed for enhanced stability and increased biological activity. The substitution of arginine at position 3 and the extended amino acid sequence significantly prolong its half-life, allowing for longer-lasting effects in cellular growth studies. IGF-1 LR3 is of research interest in studies involving tissue regeneration, muscle growth, and cellular differentiation.
– Form: Lyophilized peptide
– Purity: >99%
– Origin: Manufactured and tested in the USA
– Certifications: Certificate of Analysis (COA) included
Mechanism of Action (MOA)
IGF-1 LR3 binds to IGF-1 receptors with high affinity, stimulating anabolic activity such as protein synthesis, cellular proliferation, and glucose uptake. Due to its extended half-life, it provides prolonged stimulation of these pathways compared to native IGF-1. It also inhibits apoptosis and supports repair in muscle and nerve tissues.
Research Applications
– Muscle hypertrophy and recovery
– Tissue repair and regeneration
– Aging and neuroprotective studies
– Bone growth and cellular repair models
– Insulin sensitivity and glucose metabolism research
Key Benefits for Research
– Extended half-life (~20–30 hours vs. native IGF-1’s ~20 minutes)
– Enhanced bioavailability and activity
– Supports recovery and cellular repair
– Versatile applications across regenerative research models
Certificate of Purity & Testing
Each vial is:
– Produced in a GMP-compliant U.S. facility
– Accompanied by a Certificate of Analysis (COA)
– Verified using mass spectrometry and HPLC
– Shipped securely with cold-chain protocols if needed
Formulation & Dosage Info
– Contents: 1mg IGF-1 LR3 lyophilized powder
– Appearance: White or off-white powder
– Solubility: Reconstitute with sterile bacteriostatic water
– Storage: Store lyophilized at -20°C; use within 30 days after reconstitution
*For research use only. Not for human or veterinary use.*
Legal & Compliance Notices
– Sold for research and laboratory use only
– Not intended for human or animal use
– Researchers assume all responsibility for handling and compliance
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