Humanin

Description

High-Level Summary

Humanin is a short mitochondrial-derived peptide (MDP) originally discovered for its ability to protect neurons from various stressors. It plays a role in modulating apoptosis, oxidative stress, and cellular metabolism. Humanin has become a focus in longevity, metabolic, and neurodegenerative research due to its ability to preserve mitochondrial integrity and inhibit pro-apoptotic signals.

– Form: Lyophilized peptide
– Purity: >99%
– Origin: Manufactured and tested in the USA
– Documentation: Certificate of Analysis (COA) included

Mechanism of Action (MOA)

Humanin exerts its effects by interacting with pro-apoptotic proteins (e.g., Bax, IGFBP-3) and binding to membrane receptors involved in cell survival pathways. It helps regulate mitochondrial function, reduces oxidative stress, and suppresses inflammatory signaling. These properties contribute to its potential in preserving neuronal health, delaying age-related decline, and enhancing metabolic balance.

Research Applications

– Neurodegenerative disease models (e.g., Alzheimer’s, Parkinson’s)
– Aging and longevity studies
– Mitochondrial dysfunction research
– Insulin resistance and metabolic studies
– Apoptosis inhibition and cellular repair

Key Benefits for Research

– Protects cells from oxidative and apoptotic stress
– Preserves mitochondrial function and energy balance
– Potential cognitive support in aging models
– Modulates inflammatory and metabolic pathways

Certificate of Purity & Testing

Each vial is:
– Produced in a GMP-compliant U.S. facility
– Accompanied by a Certificate of Analysis (COA)
– Verified via HPLC and mass spectrometry
– Securely shipped with quality-control documentation

Formulation & Dosage Info

– Contents: 5mg Humanin lyophilized peptide
– Appearance: White to off-white powder
– Solubility: Reconstitute with sterile bacteriostatic water
– Storage: Store at -20°C; refrigerate after reconstitution and use within 30 days
*For research use only. Not for human or veterinary consumption.*

Legal & Compliance Notices

– Intended for laboratory research only
– Not approved for human consumption or clinical use
– Buyer assumes all responsibility for legal research use