Epitalon (Epithalon)

Description

High-Level Summary

Epitalon (also known as Epithalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) originally developed by the St. Petersburg Institute of Bioregulation and Gerontology. It has gained interest for its reported ability to activate telomerase, an enzyme that maintains the length and integrity of telomeres—the protective caps on the ends of chromosomes. By preventing telomere shortening, Epitalon is under investigation for its potential role in longevity, cellular health, and age-related disease models.

– Form: Lyophilized peptide
– Purity: >99%
– Origin: Manufactured and lab-tested in the USA
– Documentation: Certificate of Analysis (COA) included

Mechanism of Action (MOA)

Epitalon activates the enzyme telomerase in somatic cells, which helps repair and extend telomeres. By maintaining telomere length, cells can divide more times before reaching senescence, which may delay cellular aging. It may also modulate melatonin secretion and antioxidant activity, contributing to circadian rhythm regulation and oxidative stress defense.

Research Applications

– Longevity and aging models
– Telomere biology and chromosomal stability
– Age-related disease research
– Cellular senescence and DNA repair studies
– Pineal gland and circadian rhythm modulation

Key Benefits for Research

– Promotes telomere stability and length
– Supports cell longevity and genomic integrity
– Exhibits antioxidant and melatonin-modulating properties
– Ideal for aging and DNA-repair-based research models

Certificate of Purity & Testing

Each vial is:
– Produced in a GMP-compliant U.S. facility
– Accompanied by a Certificate of Analysis (COA)
– Verified via HPLC and mass spectrometry
– Shipped securely with quality-control documentation

Formulation & Dosage Info

– Contents: 10mg Epitalon lyophilized peptide
– Appearance: White to off-white crystalline powder
– Solubility: Reconstitute with sterile bacteriostatic water
– Storage: Store lyophilized at -20°C; refrigerate after reconstitution and use within 30 days
*For research use only. Not for human or veterinary consumption.*

Legal & Compliance Notices

– Intended for laboratory research only
– Not approved for human consumption or clinical use
– Buyer assumes all responsibility for research use and compliance