Cagrilintide

Description

High-Level Summary

Cagrilintide is a long-acting amylin analog developed to study appetite regulation, delayed gastric emptying, and energy homeostasis. As an investigational peptide, it mimics the natural hormone amylin, co-secreted with insulin from pancreatic β-cells, and plays a critical role in postprandial glucose control and satiety signaling. Cagrilintide is often researched alone or in combination with GLP-1 analogs to investigate synergistic effects in weight regulation and metabolic syndromes.

– Form: Lyophilized peptide
– Purity: ≥99%
– Origin: Manufactured and tested in the USA
– Certifications: Certificate of Analysis (COA) included with every order

Mechanism of Action (MOA)

Cagrilintide binds to amylin receptors in the brain and gastrointestinal tract, where it:
– Slows gastric emptying to prolong digestion and nutrient absorption
– Increases satiety signals via the area postrema in the brainstem
– Decreases food intake and modulates caloric consumption
– Works synergistically with GLP-1 analogs to enhance metabolic benefits

Research Applications

– Amylin receptor signaling studies
– Appetite suppression and satiety models
– Delayed gastric emptying and gut-brain axis research
– Obesity and weight loss combination therapies
– Synergy studies with GLP-1 receptor agonists

Key Benefits for Research

– Long-acting formulation for sustained receptor activation
– Ideal for combination protocols with incretin-based analogs
– Validated in animal and translational models of obesity
– Ultra-high purity for reproducibility in controlled studies

Certificate of Purity & Testing

Each vial is:
– Manufactured in a GMP-compliant U.S. facility
– Accompanied by a Certificate of Analysis (COA)
– Subjected to HPLC and mass spectrometry verification
– Shipped from within the United States for quality control

Formulation & Dosage Info

– Contents: 5mg of lyophilized Cagrilintide peptide
– Appearance: White/off-white powder
– Solubility: Sterile bacteriostatic water or acetic acid recommended
– Storage: Store lyophilized vial at -20°C; reconstituted solution stable up to 30 days when refrigerated
*For laboratory research use only. Not intended for human or veterinary use.*

Legal & Compliance Notices

– This product is sold for research purposes only
– Not for human consumption, injection, or diagnostic procedures
– Must be handled by qualified professionals in accordance with institutional and governmental safety guidelines